The University of Saskatchewan values diversity, and Aboriginal engagement is a strategic priority.

Postdoctoral Position - Clinical Metabolomics of Asthma and other Respiratory Diseases

Department of Pediatrics and College of Pharmacy and Nutrition

Primary Focus: We have developed LC-MS-MS methods to analyze urine patient samples in relation to their clinical presentation.  We are looking for a researcher to perform LC-MS analysis of a large number of adult and children urine samples, followed by in-depth statistical analysis to determine the important metabolites that could serve as diagnostic and prognostic biomarkers.  We are also at a stage of larger scale clinical trials, so expertise in grant writing and study design would be an asset.

Requirements:  We are seeking outstanding individuals with a Ph.D. degree in analytical chemistry with a required experience in LC-MS metabolomics and statistical analysis of biological samples  Enthusiasm for top-quality research and the ability to work in a multidisciplinary team is expected. Eligibility for tri-council postdoctoral fellowship funding is favorable. We are also willing to consider applicants looking for a Research Scientist level if a post-doctoral position is not possible.

Background:  Diagnosing allergic diseases (like asthma) and monitoring the response to therapy can be difficult for doctors in a typical primary care setting.  Valid, reliable, noninvasive tests are not available, especially in children.  Instead, doctors rely on trial and error, an approach, which too often diagnoses patients and is wasteful economically.  Metabolomics is the study of small molecules generated from cellular metabolic activity.  Diseased tissues create unique changes in cellular metabolic pathways. Asthma has unique airway cell pathology compared to the airways of healthy subjects or those with diseases like chronic obstructive pulmonary disease (COPD).  Even cells outside the lung (e.g. muscles, brain) are affected by lung disease (e.g. work of breathing). Thus, more severe airway disease causes more cellular stress.  Since 2009, our hypothesis has been that the pattern of metabolites created reflects whether you have a chronic respiratory disease, what type of respiratory disease, and how severe it is that day.  As such, we are developing a urine test that a doctor could use.

Conditions:  Compensation will be at the postdoctoral level in Canada.  The initial term will be for one year and can be renewed for one additional year based on performance.

How to Apply:

Qualified applicants should send their curriculum vitae to Dr. Adamko at darryl.adamko@usask.ca

Application review will begin immediately and will continue until the position is filled.

Contact:              

Darryl Adamko
Department of Pediatrics
University of Saskatchewan
Saskatoon, SK
Canada

Email: darryl.adamko@usask.ca

 

 

 

 

 

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The University of Saskatchewan is strongly committed to a diverse and inclusive workplace that empowers all employees to reach their full potential. All members of the university community share a responsibility for developing and maintaining an environment in which differences are valued and inclusiveness is practiced. The university welcomes applications from those who will contribute to the diversity of our community. All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

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